ppbNeurobiological Laboratory, Department of Neurology and Clinical Neurophysiology, The Neurology Department, St. Olavs Hospital /b /ppThe Neurobiological Laboratory lead by Associate Professor Katja Scheffler is looking for a motivated postdoctoral fellow/researcher who is passionate about bridging clinical and basic research in neuroscience. /ppOur lab investigates novel molecular mechanisms of genome regulation that play a critical role in brain function. A key focus of our work is to identify new diagnostic tools and therapeutic interventions for neurodegenerative diseases such as Alzheimer’s disease (AD). /ppAs a successful candidate, you will be working on optimizing human organoids to model neurodegenerative diseases and better understanding disease mechanism by multi-omics analysis. This includes but is not limited to generating organoids from patient-derived iPSCs, extraction and processing of nucleic acids and proteins, confocal imaging, and bioinformatics for interpretation and integration of single-cell transcriptomics and epigenomic datasets. /ppThe project will be in close collaboration with Prof. Magnar Bjørås and his recent start up Zenit Science. /ppThe period of employment for the position is 2 years, starting as soon as possible. /ppbApplication /b /ppThe application and all attachments must be in English and include: /pulliLetter of motivation /liliCV (including a list of publications) /liliCopy of your original academic degree(s) /liliNames and contact information of at least two relevant referees /liliCarry out research of high quality within the framework described above /liliAcademic publications and popular science dissemination /liliPresent findings at national and international conferences /liliMaintain documentation of analysis pipelines (GitHub, Jupyter, R Markdown) /liliCo-supervise PhD and master’s students within the research team /liliApply for research grants /li /ulh3Qualifications /h3ulliAcademically relevant background within molecular biology, cell biology, neuroscience, biotechnology or related subjects /liliPhD degree in neuroscience, neurobiology, molecular and cell biology or related field /liliStrong experimental skills in cell culture, immunostaining, and imaging techniques /liliHands-on experience with genomics, transcriptomics or related omics-based workflows /liliProficiency in R and/or Python and familiarity with Unix-based systems /liliFamiliarity with bioinformatics tools and libraries (Bioconductor, Seurat, Scanpy) /liliStrong scientific writing skills, with a track record of peer-reviewed publication /liliStrong personal initiative, self-motivation and work ethic /liliProactive and solution-oriented mindset, with the ability to contribute to a dynamic and interdisciplinary research team /liliExcellent communication and organizational skills /liliAbility to work collaboratively to accomplish common research goals /li /ulh3We offer /h3ulliAn exciting job with an important mission in society /liliMeaningful tasks in a strong and international professional environment /liliGuidance for career development /liliOpen and inclusive working environment with committed colleagues /liliSalary according to current tariff /liliPublic pension scheme with beneficial insurance schemes and mortgages in KLP /li /ul /p #J-18808-Ljbffr
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